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Fountain of Life

What is Fountain of Life?

Fountain of Life is nature's most powerful lignan source, providing a strong antioxidant supply to protect us against free radicals. It is your best source to create enterolactone as this lignan is in aglycone form that is readily absorbed in the body and converted efficiently to enterolactone.

Benefits of Fountain of Life

Nature's most potent lignan source. Harvested from the knotwood of Picea abies, the Norwegian Spruce, and rich in 7-hydroxymatairesinol (HMR), one of the most researched plant lignans in modern science.

NPN #80004596 — Health Canada Licensed Natural Health Product
15+
distinct lignans identified in Norway spruce knotwood
92%
reduction in TNF-alpha inflammation marker in research
63%
reduction in hot flashes in clinical pilot study (8 weeks
High blood Pressure Support Cardiovascular​

Fountain of Life supports healthy blood pressure already within a normal range. The HMR lignans in Norwegian Spruce Extract help reduce oxidative stress on blood vessel walls — a key contributor to elevated pressure — and support endothelial function, the health of the inner lining of arteries that regulates vessel tone and flexibility.

Higher dietary lignan intake is associated in observational research with lower rates of cardiovascular disease-related mortality and improved vascular function over time.

How it works: HMR converts in the gut to enterolactone, which circulates in the bloodstream and exerts antioxidant, anti-inflammatory effects on vascular endothelial cells — reducing arterial stiffness and supporting healthy circulation.
Arthritis and joint pain relief Musculoskeletal - Click To Read More

Arthritis — whether osteoarthritis (mechanical wear) or rheumatoid arthritis (immune-driven inflammation) — involves the same inflammatory cytokines that Norwegian Spruce lignans directly target. By reducing IL-1β and TNF-alpha at the cellular level, Fountain of Life addresses the biological drivers of joint swelling, stiffness, and pain rather than simply masking symptoms.

The antioxidant activity of HMR also helps neutralize free radicals that degrade cartilage — supporting longer-term joint health and mobility.

Pathway: Reduction of MMP-3 (a matrix metalloproteinase that breaks down cartilage and connective tissue) helps slow the physical degradation of joint structures.
Inflammation reduction Immune and Inflammatory - Click To Read More

Chronic inflammation is the root driver of dozens of modern diseases — from arthritis and heart disease to diabetes and autoimmune conditions. HMR lignans in Fountain of Life are among the most potent natural anti-inflammatory compounds studied, shown to inhibit three major inflammation pathways simultaneously.

Research identified that spruce resin is a strong inhibitor of interleukin-1 beta (IL-1β), matrix metalloproteinase-3 (MMP-3), and TNF-alpha — with anti-inflammatory potential described as superior to low-dose dexamethasone (a pharmaceutical corticosteroid) in controlled lab settings.

How it works: HMR and HMR2 lignans attenuate nuclear factor-κB (NF-κB) signalling — the master switch of the inflammatory response — reducing the production of adhesion molecules that draw inflammatory cells to tissues.
Hormone balance Endocrine

Fountain of Life is one of the richest natural sources of lignans — phytoestrogens that interact with the body’s estrogen receptors in a protective, balancing way. Unlike synthetic hormones, HMR binds preferentially to estrogen receptor beta (ERβ), which tends to have protective rather than proliferative effects on cells.

This makes Norwegian Spruce Extract particularly valuable for women experiencing hormonal imbalance — whether from perimenopause, menopause, or general estrogen fluctuation — as it provides gentle hormonal signalling without the risks associated with hormone replacement therapy.

How it works: HMR is metabolized into enterolactone by gut bacteria. Enterolactone acts as a selective estrogen receptor modulator (SERM) — binding receptors with a tissue-selective effect that moderates estrogen activity where it is too high or too low.
Menstrual cramps and period discomfort Women's Health

Period pain (dysmenorrhea) is driven by prostaglandins — inflammatory compounds released by the uterine lining that cause painful contractions. The anti-inflammatory action of HMR lignans directly addresses the prostaglandin-driven inflammation underlying menstrual cramps, helping to reduce the intensity of uterine spasms and associated lower back pain.

The hormone-balancing effect of enterolactone also helps regulate the cycle itself — moderating estrogen dominance, which is a common contributor to heavier, more painful periods.

Pathway: Inhibition of IL-1β and TNF-alpha reduces the inflammatory cascade that amplifies prostaglandin production — addressing cramp severity at its biochemical root.
Menopause, hot flashes and night sweats Women's Health

A clinical pilot study found that supplementation with HMR lignan from Norway Spruce produced a 63% reduction in hot flash frequency in postmenopausal women after 8 weeks at the higher dose. Even at four weeks, a 37% reduction was observed at the same dose.

Unlike flaxseed lignans, which often cause gastrointestinal side effects, HMR from Norwegian Spruce produced only one adverse event in the entire study with no dropouts — making it one of the most tolerable natural phytoestrogen options for menopausal support.

Evidence: U.S. clinical pilot, 20 postmenopausal women, 8 weeks. Average hot flashes reduced from 4.3 per day to 2.0 per day at the 50mg dose. Serum enterolactone increased 3-fold within 24 hours of supplementation.
Open wound healing and skin regeneration Tissue Repair

Norwegian Spruce resin and its lignans have been used in wound healing since antiquity in Nordic folk medicine — and modern clinical research has validated this tradition. Since 2002, a multidisciplinary research group has studied Norway Spruce resin in wound care, finding substantial antimicrobial, wound-healing, and skin regeneration properties.

The lignan pinoresinol specifically was identified as the component responsible for enhancing keratinocyte proliferation — the skin cells responsible for re-epithelialization and wound closure. Lignans also suppress TNF-alpha and IL-1β in wound tissue, reducing the inflammatory environment that slows healing.

Clinical evidence: Spruce resin salve improved healing of pressure ulcers, complicated surgical wounds, and diabetic foot ulcers in clinical trials. Active against MRSA and vancomycin-resistant bacteria — effective where standard antibiotics fail.
Antimicrobial and antifungal protection Tissue Repair

Fountain of Life supplement demonstrates antimicrobial activity against a broad range of bacteria, both gram-positive and gram-negative  including antibiotic-resistant strains such as MRSA and VRE (vancomycin-resistant Enterococcus). The resin acids break down bacterial cell walls and membranes, preventing energy production and causing cell death.

Antifungal activity has been demonstrated against multiple pathogenic species, including those responsible for skin and nail infections (onychomycosis). Research showed inhibition rates of 30–100% against tested fungal pathogens depending on concentration.

Mechanism: Resin acids disrupt microbial cell membranes. HMR lignan adds antifungal activity through separate pathways. The combined effect covers a wider spectrum than either component alone.
Bone density and osteoporosis prevention Skeletal

Estrogen plays a critical role in maintaining bone density — which is why postmenopausal women face elevated osteoporosis risk as estrogen declines. The phytoestrogenic activity of HMR lignans supports bone-building osteoblast activity and helps moderate the bone-resorbing activity of osteoclasts.

Research has found that pinoresinol (a lignan in spruce extract) promotes osteoblast proliferation in vitro — directly supporting the cellular mechanisms of bone formation and density maintenance.

Pathway: Enterolactone binds estrogen receptor beta in bone cells, moderating the estrogen-dependent signalling that regulates bone turnover and density preservation.
Antioxidant protection and free radical defence Cellular Health

Norwegian Spruce Extract delivers high-performance antioxidants that neutralize free radicals — unstable molecules that cause oxidative damage to cells, DNA, proteins, and lipids. This oxidative damage is a primary driver of aging, chronic disease, and reduced cellular function.

HMR lignans have demonstrated strong antioxidant activity in vitro, inhibiting lipid oxidation and protecting cell membranes from oxidative degradation. The antioxidant effect is active both before and after conversion to enterolactone, providing two protective phases.

Application: The antioxidant capacity of HMR extends to cardiovascular, neurological, and metabolic protection — reducing the cellular burden of oxidative stress across multiple organ systems simultaneously.
Cancer risk reduction support Chemo-preventive

Epidemiological studies consistently link higher dietary lignan intake and higher blood enterolactone levels with lower rates of hormone-dependent cancers — particularly breast cancer and prostate cancer. In studies on postmenopausal women, healthy enterolactone levels correlated with significantly lower rates of breast cancer incidence.

HMR’s selective binding to estrogen receptor beta (rather than alpha) means it may limit estrogen-driven cell proliferation — a mechanism implicated in hormone-receptor-positive breast cancer — without blocking the beneficial effects of estrogen in other tissues.

Note: These are observational and mechanistic findings. Fountain of Life is not intended to diagnose, treat, or prevent cancer. Consult your healthcare provider for guidance on cancer risk management.
Cholesterol and metabolic syndrome - Metabolic

Growing evidence suggests HMR lignans positively influence lipid metabolism — the body’s processing and balancing of cholesterol and fats. Observational research on dietary lignan intake links higher consumption with reduced LDL (bad) cholesterol, reduced LDL oxidation, and better overall lipid profiles.

For individuals with metabolic syndrome — a cluster of conditions including abdominal weight, high blood pressure, elevated blood sugar, and abnormal cholesterol — lignan supplementation represents a multi-target natural intervention addressing several risk factors simultaneously.

Pathway: Enterolactone modulates cholesterol biosynthesis pathways and reduces vascular inflammation — two of the key mechanisms underlying metabolic syndrome and its cardiovascular consequences.
Gut microbiome and digestive health - Digestive

The therapeutic activity of HMR lignans is intimately connected to gut microbiome health. The conversion of HMR into the active mammalian lignan enterolactone is performed by specific intestinal bacteria — Clostridium scindens and related species. A healthy, diverse gut flora therefore amplifies the benefits of Fountain of Life.

Unlike flaxseed-derived lignans, HMR from Norwegian Spruce is far better tolerated digestively — producing minimal bloating, gas, or gastrointestinal discomfort, making it suitable for individuals with sensitive digestive systems.

Key advantage: Serum enterolactone levels increase 3-fold within 24 hours of HMR supplementation and remain elevated for up to 72 hours — providing sustained systemic benefit from a single daily dose.
Cognitive function and neurological support - Neurological

Phytoestrogens including lignans are associated in research with cognitive function support — particularly in areas regulated by estrogen, such as memory, verbal fluency, and mood regulation. The anti-inflammatory and antioxidant properties of HMR also reduce neuroinflammation, a contributor to cognitive decline and neurodegenerative conditions.

The reduction of systemic oxidative stress through lignan supplementation supports overall neurological health and may help moderate the mental fog and mood fluctuations associated with hormonal transitions including menopause.

Supporting research: Lignans have been studied in the context of immunity, inflammation, reproduction, fertility, and cognitive function — reflecting their broad hormonal and anti-inflammatory reach across body systems.
Oral and periodontal health - Oral Health

Recent research evaluated Norway Spruce resin extract as a natural agent for periodontal care, finding anti-inflammatory properties in macrophage-like cells, anti-plaque efficacy against streptococci, and strong biocompatibility with human gingival tissue.

The antimicrobial activity of spruce lignans against the bacteria responsible for plaque, gingivitis, and periodontal disease — combined with the anti-inflammatory reduction of gum tissue irritation — suggests a complementary role in oral health maintenance.

Research note: Spruce resin extract inhibited expression of TNF-alpha and IL-1β in periodontal tissue models — the same inflammatory markers implicated in gum disease progression.
Energy, vitality and immune resilience - General Wellness

By reducing the chronic inflammatory load that quietly drains energy, moderating hormonal fluctuations that disrupt sleep and mood, and providing cellular protection from oxidative stress, Fountain of Life supports the foundational conditions for sustained daily energy and vitality.

The immunomodulatory activity of HMR — demonstrated through its dose-dependent regulation of monocyte and white blood cell inflammatory responses — also supports balanced immune function, helping the body respond appropriately to threats without chronic over-activation.

Daily use: As a liquid dropper supplement, Fountain of Life is absorbed rapidly and conveniently — making it easy to maintain the consistent daily supplementation that delivers cumulative, long-term benefit.

This information is for educational purposes and reflects published scientific and clinical research on Norwegian Spruce extract (Picea abies) and its primary active compound 7-hydroxymatairesinol (HMR lignan). Fountain of Life Norwegian Spruce Extract is a licensed Natural Health Product (NPN # 80004596) that supports overall cardiovascular health and healthy blood pressure already within a normal range.

This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified healthcare professional before use if you are pregnant, breastfeeding, taking medications, or have a medical condition. Individual results may vary. Research cited includes in vitro, in vivo, and clinical pilot studies — not all findings have been confirmed in large-scale human trials. <br><br>

Fountain of Life — 100% Natural · Non-GMO · Made in Canada · Health Canada Licensed